Non-coding rna in rhabdomyosarcoma progression and metastasis

HIGHLIGHTS

  • who: Farah Ramadan from the StJohn's University, United States have published the research work: Non-coding RNA in rhabdomyosarcoma progression and metastasis, in the Journal: (JOURNAL)

SUMMARY

    The term oncomiR applies to a miRNA that inhibits the expression of tumor suppressive genes and further promotes cell growth and survival; thus, tumor-suppressive miRNA are those whose expression in cancer cells and the tumor microenvironment is often down-regulated to escape anti-cancer mechanisms. Using gene and proteomic profiling, low levels of PAX7 transcript and protein were found to be necessary for miR . . .

     

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