Non-coding stem-bulge rnas are required for cell proliferation and embryonic development in c. elegans

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  • who: RNAs during DNA replication from the (UNIVERSITY) have published the paper: Non-coding stem-bulge RNAs are required for cell proliferation and embryonic development in C. elegans, in the Journal: (JOURNAL) of 28/Nov/2014
  • what: The authors report the first functional characterisation of nematode sbRNAs. The authors demonstrate that sbRNAs from a range of nematode species are able to reconstitute the initiation of chromosomal in the presence of proteins in vitro and that conserved nucleotide sequence motifs are essential for this function. By functionally inactivating sbRNAs with antisense morpholino oligonucleotides the authors show . . .

     

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