HIGHLIGHTS
SUMMARY
Antiphospholipid syndrome (APS) is reserved for patients who develop vascular thrombosis in association with aPL or a lupus anticoagulant (LAC), which screens indirectly for the presence of aPL. A positive LAC detects in_vitro inhibition of the phospholipid-dependent steps of the coagulation cascade. This nomenclature is often confusing to clinicians since these autoantibodies are pro-coagulant in_vivo but prolong this coagulation test in_vitro. In these cases, non-criteria aPL (NC-aPL) may be responsible for LAC positivity. In the following single-center case series, NC-aPL testing was obtained in individual patients due to . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.