Nonclassical phenyl bioisosteres as effective replacements in a series of novel open-source antimalarials

HIGHLIGHTS

• who: Edwin G. Tse et al. from the H) (alcohol OH signal not seen) have published the research: Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials, in the Journal: (JOURNAL) of July/17,/2020
• what: The authors show the successful incorporation of a range of phenyl bioisosteres during the opensource optimization of an antimalarial series.

SUMMARY

Following the procedure of Aleksandrov et_al:61 Compound S5 (65.0 mg, 0.23 mmol) was dissolved in a mixture of AcOH (0.5 mL) and conc. Following the . . .

 



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