Nonmalignant ar-positive prostate epithelial cells and cancer cells respond differently to androgen

HIGHLIGHTS

  • who: Endocrine-Related and collaborators from the of Medicine and Health Technology, Tampere University and Tays Centre, Tampere University Hospital, Tampere, Finland have published the Article: Nonmalignant AR-positive prostate epithelial cells and cancer cells respond differently to androgen, in the Journal: (JOURNAL)
  • what: By transcriptional characterization and comparison to the PCa cell lines LNCaP and LNCaPARhi, which mimic late-stage castration-resistant PCa, the authors show that the RWPE-1-AR cell line is useful as a nonmalignant, AR-positive prostate epithelial_cell model for studying the transformation of the prostate epithelium.
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