Nonnegative spatial factorization applied to spatial genomics

HIGHLIGHTS

  • who: F. William Townes from the (UNIVERSITY) have published the Article: Nonnegative spatial factorization applied to spatial genomics, in the Journal: (JOURNAL) of 11/Oct/2021
  • what: The authors show how to combine spatial and nonspatial factors with the hybrid model NSFH.
  • how: The authors examined the biological relevance of nonnegative factorization by focusing on the NSFH model with M=3000 IPs and L=20 components (ten spatial and ten nonspatial).
  • future: A promising future direction for extending GPs to even larger numbers of observations is the nearest-neighbor approximation2122.
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