Nonsteroidal mineralocorticoid receptor antagonism by finerenone—translational aspects and clinical perspectives across multiple organ systems

HIGHLIGHTS

• who: Peter Kolkhof and colleagues from the , Wuppertal, Germany Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Attikon have published the paper: Nonsteroidal Mineralocorticoid Receptor Antagonism by Finerenoneu2014Translational Aspects and Clinical Perspectives across Multiple Organ Systems, in the Journal: (JOURNAL)
• what: The authors provide an overview of the pathophysiologic role of MR overactivation and preclinical evidence with the nonsteroidal MRA in a range of different disease models with respect to major components of the aggregate mode of action including interfering with reactive oxygen species generation inflammation fibrosis and hypertrophy. The authors . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.