Nonsynaptic junctions on myelinating glia promote preferential myelination of electrically active axons

HIGHLIGHTS

  • who: Hiroaki Wake from the (UNIVERSITY) have published the article: Nonsynaptic junctions on myelinating glia promote preferential myelination of electrically active axons, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 29/04/2015
  • what: The authors show using an in vitro system that oligodendrocytes preferentially myelinate electrically active axons but synapses from axons onto myelin-forming oligodendroglial cells are not required.
  • how: In the present experiments calcium imaging electron microscopy and electrophysiology were used to determine the involvement of axon-glia communication in myelination of electrically active axons in_vitro. Consistent with the hypothesis . . .

     

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