Nontraditional roles of dna polymerase eta support genome duplication and stability

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  • who: Kristin A. Eckert from the Gittlen Cancer Research Laboratories, Department of Pathology, Penn State University College of Medicine have published the Article: Nontraditional Roles of DNA Polymerase Eta Support Genome Duplication and Stability, in the Journal: Genes 2023, 14, 175. of /2023/
  • what: Since this discovery, the majority of the research regarding Pol u03b7`s cellular functions has focused on DNA damage response, particularly after UV irradiation. The review focuses almost exclusively on studies performed using human and mouse model systems. The authors designed a model of lagging_strand replication with RFC-loaded PCNA that . . .

     

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