Noradrenergic modulation of the piriform cortex: a possible avenue for understanding pre-clinical alzheimer`s disease pathogenesis

HIGHLIGHTS

  • who: Vishaal Rajani and Qi Yuan from the Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, StJohn`s, NL, Canada have published the research work: Noradrenergic Modulation of the Piriform Cortex: A Possible Avenue for Understanding Pre-Clinical Alzheimer`s Disease Pathogenesis, in the Journal: (JOURNAL)
  • what: The authors propose that LC degeneration at pre-clinical stages drives early olfactory deficits.
  • how: The authors presented novel results from a pretangle tau rat model and a new view that dysfunction of norepinephrine (NE) regulation in the PC may underlie preclinical stage . . .

     

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