Not all autoantibodies are clinically relevant. classic and novel autoantibodies in sjögren’s syndrome: a critical review

HIGHLIGHTS

SUMMARY

    The development of ectopic GCs on the site of inflammation, often within the salivary glands, has been associated with a higher frequency of local production of anti-Ro/SSA and anti-La/SSB autoantibodies in SjS patients. Contrary to what happens in the bone marrow, BAFF has an effect in B-cells tolerance at the periphery, with increased levels of circulating BAFF leading to a Frontiers in Immunology Classic autoantibodies in Sjögren`s syndrome Anti-nuclear antibodies (ANA) ANA are antibodies that target antigens in the nucleus of the cell. 10.3389/fimmu . . .

     

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