Notch-associated lncrnas profiling circuiting epigenetic modification in colorectal cancer

HIGHLIGHTS

  • who: Omnia Emam from the Biochemistry Department, Faculty of Pharmacy, Ain Shams University have published the paper: Notch-associated lncRNAs profiling circuiting epigenetic modification in colorectal cancer, in the Journal: (JOURNAL)

SUMMARY

    Positive association has been shown between the Notch receptor, Notch1, expression and deeper invasion of tumor-lymph node-metastasis (TNM) in CRC. LncRNAs are nonprotein producing transcripts, performing a crucial role in the epigenetic regulation(s) affecting gene_expression. LncRNAs can control Notch-activation through regulation of Notch receptors or Notch ligands expression, either on transcriptional or post-transcriptional levels. Non‑protein . . .

     

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