Notch signaling induced by endoplasmic reticulum stress regulates cumulus-oocyte complex expansion in polycystic ovary syndrome

HIGHLIGHTS

  • who: Hiroshi Koike et al. from the Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Hongo, Bunkyo have published the research work: Notch Signaling Induced by Endoplasmic Reticulum Stress Regulates Cumulus-Oocyte Complex Expansion in Polycystic Ovary Syndrome, in the Journal: Biomolecules 2022, 1037 of /2022/
  • what: The authors focused on Notch2 among the four Notch receptors (Notch1-4) since it is most abundantly expressed in granulosa cells of human antral and preovulatory follicles . This study shows that expression of Notch2 and the Notc The study shows that the UPR branch . . .

     

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