Notch signaling pathway promotes th17 cell differentiation and participates in thyroid autoimmune injury in experimental autoimmune thyroiditis mice

HIGHLIGHTS

• who: Autoimmune Thyroiditis Mice and collaborators from the Department of Endocrinology and Metabolism, Binzhou Medical University Hospital, No, Second Huanghe Road, Binzhou, China have published the paper: Notch Signaling Pathway Promotes Th17 Cell Differentiation and Participates in Thyroid Autoimmune Injury in Experimental Autoimmune Thyroiditis Mice, in the Journal: Mediators of Inflammation
• what: Taken together, the present findings suggested that the Notch signaling pathway may participate in thyroid autoimmune injury by promoting the differentiation of Th17 cells and enhancing their inflammatory effect.
• future: In-depth studies on the precise pathogenesis of AIT are necessary . . .
  

   

  

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