Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin

HIGHLIGHTS

• who: Molecule Survivin and colleagues from the de Médecine, France¤b Current address: Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America have published the Article: Notch2 Signaling Sensitizes Endothelial Cells to Apoptosis by Negatively Regulating the Key Protective Molecule Survivin, in the Journal: (JOURNAL) of December/11,/2009
• what: This study investigated regulation of Notch2 and further examined its implication in EC dysfunction. Methodology/Principal Findings: Here the authors provide evidence for a novel link between Notch and TNF signaling where Notch2 is upregulated and activated in response . . .
  

   

  

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