Novel benzylidene benzofuranone analogues as potential anticancer agents: design, synthesis and in vitro evaluation based on cdk2 inhibition assays

HIGHLIGHTS

• who: Aravinda Pai from the Department of Pharmaceutical Chemistry, Manipal College Education, Manipal, Karnataka, India have published the paper: Novel benzylidene benzofuranone analogues as potential anticancer agents: design, synthesis and in vitro evaluation based on CDK2 inhibition assays, in the Journal: (JOURNAL)
• what: In this work new series of benzylidene were designed synthesized and evaluated for their antioxidant anti-colorectal cancer activity. Molecular docking MMGBSA and molecular dynamics studies were conducted to assess their binding affinity at the active site of Based on the cytotoxicity exhibited by test compounds the compound NISOA4 (from isopropyl series . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.