Novel complex of pd-l1 aptamer and holliday junction enhances antitumor efficacy in vivo

HIGHLIGHTS

• who: Ting Li et al. from the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College have published the research work: Novel Complex of PD-L1 Aptamer and Holliday Junction Enhances Antitumor Efficacy in Vivo, in the Journal: Molecules 2021, 26, 1067. of /2021/
• what: The authors designed a DNA nanostructure that had four PD-L1 aptamers built into it.
• how: The results indicated that phosphorothioate modification could significantly improve nuclease resistance and serum stability and possibly prolong the circulation time of Apt-HJ. The results indicated . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.