Novel curcumin inspired bis-chalcone promotes endoplasmic reticulum stress and glioblastoma neurosphere cell death

HIGHLIGHTS

  • who: Lorenzo Sansalone and collaborators from the Department of Chemistry, University of Miami, Memorial Drive, Coral Gables, FL, USA have published the paper: Novel Curcumin Inspired Bis-Chalcone Promotes Endoplasmic Reticulum Stress and Glioblastoma Neurosphere Cell Death, in the Journal: (JOURNAL)
  • what: Despite advances in neuroimaging and neurosurgical techniques, and an abundance of research aimed at understanding and targeting cell-signaling pathways driving GBM pathogenesis, GBM remains one of the most lethal brain tumors.

SUMMARY

    The authors and examined their effect on GBM stem_cells (GSCs). Patient derived GSCs have been shown . . .

     

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