HIGHLIGHTS
- who: W. Hayes McDonald from the (UNIVERSITY) have published the paper: Novel Essential DNA Repair Proteins Nse1 and Nse2 Are Subunits of the Fission Yeast Smc5-Smc6 Complex*, in the Journal: (JOURNAL) of August/11,/2003
- what: The authors show that both Nse1 and Nse2 interact with Smc5 in_vivo, as part of the Smc5- 6 complex.
- how: The mass spectrometry data showed that Nse1 Nse2 and Smc6 stably co-precipitated with Smc5-TAP.
SUMMARY
The SMC heterodimers do not function alone and must associate with essential non-SMC subunits . . .
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