Novel generation of fap inhibitor-based homodimers for improved application in radiotheranostics

HIGHLIGHTS

  • who: Marcel Martin and collaborators from the Department of Chemistry-TRIGA Site, Johannes Gutenberg University Mainz, Mainz, Germany have published the research work: Novel Generation of FAP Inhibitor-Based Homodimers for Improved Application in Radiotheranostics, in the Journal: (JOURNAL)
  • what: Radioligand therapy (RLT) with radiometals such as lutetium-177 is the main objective of these new dimers.
  • how: The new FAPi dimers were tested for their in_vitro affinity for FAP as well as PREP DPP4 DPP8 and DPP9.

SUMMARY

    The actual in_vivo role of FAP is not fully understood . . .

     

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