Novel insights into epigenetic reprogramming and destabilization of pericentromeric heterochromatin in cancer

HIGHLIGHTS

  • who: Morten Frier Gjerstorff from the Department of and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark have published the paper: Novel Insights Into Epigenetic Reprogramming and Destabilization of Pericentromeric Heterochromatin in Cancer, in the Journal: (JOURNAL)

SUMMARY

    Similar structures are present at other chromosomes such as 9 and 10, but these are smaller and have different satellite_DNA compositions. In most patients, this results in 1q copy numbers of 3 to 4, but in some patients a process called "1q12-21 breakage-fusionbridge cycle amplifications" can generate ladders of 1q12-21 . . .

     

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