Novel insights into rad52’s structure, function, and druggability for synthetic lethality and innovativeanticancer therapies

HIGHLIGHTS

  • who: Beatrice Balboni and colleagues from the Computational and Chemical Biology, Istituto Italiano di Tecnologia, via Morego, Genoa, Italy Department of Pharmacy and Biotechnology, University of Bologna, via Belmeloro, Bologna, Italy have published the article: Novel Insights into RAD52u2019s Structure, Function, and Druggability for Synthetic Lethality and InnovativeAnticancer Therapies, in the Journal: Cancers 2023, 1817 of /2023/
  • what: Characterizations of the most promising compounds often involve cellular experiments focused on RAD52 molecular activity, especially in BRCA-deficient cancer cells.
  • how: The in_vitro and cell-based data showed that its activity against RAD52 is . . .

     

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