Novel insights on lipid metabolism alterations in drug resistance in cancer

HIGHLIGHTS

  • who: Cancer chemoresistance and colleagues from the Hunan Hospital and the Affiliated Hospital of Xiangya School of Medicine, South University, Changsha, Changsha, China have published the article: Novel Insights on Lipid Metabolism Alterations in Drug Resistance in Cancer, in the Journal: (JOURNAL)
  • what: This study showed that selonsertib interacted with substrate-binding_sites to inhibit efflux function and increase intracellular accumulation of anticancer drugs thereby sensitizing cancer cells.

SUMMARY

    There are different kinds of chemotherapeutic agents including alkylators, antibiotics, antimetabolites, topoisomerases inhibitors, mitosis inhibitors and others (Espinosa et_al, 2003; Pan et_al, 2016 . . .

     

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