Novel long non-coding rnas associated with inflammation and macrophage activation in human

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  • who: Avisankar Chini from the DepartmentThe University have published the Article: Novel long non-coding RNAs associated with inflammation and macrophage activation in human, in the Journal: Scientific Reports Scientific Reports
  • what: The analysis showed that, LPS treatment induced the expression of both IL6 (250-fold) and IL1u03b2 (sixfold) mRNA in THP1-Mu03a6 macrophages (Fig 1B). Interestingly, the analysis demonstrated that along with well-known protein coding genes, cytokines and chemokine, LPS-stimulation of THP1-Mu03a6, also significantly affected (induction and down regulation) the expression of many noncoding RNAs. This analysis demonstrated that IL6 expression . . .

     

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