Novel mechanisms underlying inhibition of inflammation-induced angiogenesis by dexamethasone and gentamicin via pi3k/akt/nf-κb/vegf pathways in acute radiation proctitis

HIGHLIGHTS

• who: Yousong Li from the DepartmentMedical University have published the research work: Novel mechanisms underlying inhibition of inflammation-induced angiogenesis by dexamethasone and gentamicin via PI3K/AKT/NF-u03baB/VEGF pathways in acute radiation proctitis, in the Journal: Scientific Reports Scientific Reports
• what: This study aims to evaluate the effect of DXM combined with GM on ARP mice, and to further elucidate its molecular mechanisms by using transcriptome sequencing, western blot, and immunohistochemistry. To explore the specific mechanisms underlying the inflammation-induced angiogenesis, this study analyzed global gene_expression in rectal mucosa from ARP mice.
 



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