Novel mouse strains to study circulating permeability factor(s) in primary focal segmental glomerulosclerosis

HIGHLIGHTS

  • who: Dirk den Braanker et al. from the Department of Nephrology, Radboud Institute for Health Sciences, Radboud University Medical Center, Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands have published the research work: Novel mouse strains to study circulating permeability factor(s) in primary focal segmental glomerulosclerosis, in the Journal: PLOS ONE of June/26,/2022
  • what: The authors aimed to develop a FSGS-prone Thy-1.1 transgenic mouse model with accelerated proteinuria after injection of samples from patients with FSGS. The authors first established and compared 5 different Thy . . .

     

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