Novel mutations in acp5 and samhd1 in a patient with pediatric systemic lupus erythematosus

HIGHLIGHTS

• who: Dai Dai and Nan Shen from the Shanghai Institute of Rheumatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China have published the paper: Novel Mutations in ACP5 and SAMHD1 in a Patient With Pediatric Systemic Lupus Erythematosus, in the Journal: (JOURNAL)

SUMMARY

Signaling and immune cell activation or function. The authors also analyzed the synergistic regulation of these two genes and demonstrated their combined contribution to type I IFN, which suggests a pathogenic role of this genetic variant in this pSLE patient. Systemic lupus erythematosus (SLE) is a chronic . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or E-mail:

If you don't have an account, you can create one here.