Novel nanomolar allosteric modulators of ampa receptor of bis(pyrimidine) series: synthesis, biotesting and sar analysis

HIGHLIGHTS

  • who: Kseniya N. Sedenkova et al. from the Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, Moscow, Russia have published the research work: Novel Nanomolar Allosteric Modulators of AMPA Receptor of Bis(pyrimidine) Series: Synthesis, Biotesting and SAR Analysis, in the Journal: Molecules 2022, 8252 of /2022/
  • what: In this work novel bis(pyrimidines) were studied as modulators. In this connection, in the course of this work the authors aimed to obtain a broader

SUMMARY

    It wason shown that in 2 ofproperties tetrahydroquinazoline: while compounds 1a,b,don demonstrated activity . . .

     

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