HIGHLIGHTS
- who: Gabriel G. Dorighello and colleagues from the Department of Pathology, Faculty of Medical Sciences, State University of Campinas, Campinas, SP, Brazil have published the article: Novel Role of CETP in Macrophages: Reduction of Mitochondrial Oxidants Production and Modulation of Cell Immune-Metabolic Profile, in the Journal: Antioxidants 2022, 1734 of 28/07/2022
- how: Altogether the authors showed that CETP expression in macrophages decreased mitochondrial oxidant production increased mitochondrial respiratory capacity induced mitochondrial network elongation attenuated the expression of pro-inflammatory genes and decreased unesterified cholesterol content and phagocytosis activity.
SUMMARY
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