Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (trpm8) in the activation of store-operated channels in lncap human prostate cancer epithelial cells*

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  • who: Ste̕phanie Thebault from the (UNIVERSITY) have published the Article: Novel Role of Cold/Menthol-sensitive Transient Receptor Potential Melastatine Family Member 8 (TRPM8) in the Activation of Store-operated Channels in LNCaP Human Prostate Cancer Epithelial Cells*, in the Journal: (JOURNAL) of November/25,/2005
  • what: The authors show that despite such expression, LNCaP cells respond to cold/menthol stimulus by membrane current (Icold/menthol) that shows inward rectification and high Ca2ⴙ selectivity, which are dramatically different properties from "classical" TRPM8-mediated Icold/menthol. The authors demonstrate that these puzzling results arise from . . .

     

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