Novel role of the synaptic scaffold protein dlgap4 in ventricular surface integrity and neuronal migration during cortical development

HIGHLIGHTS

• who: Delfina M. Romero from the 1270, France, Sorbonne University have published the article: Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development, in the Journal: Neurology, CHU Amiens, Amiens, France. 6
• what: The authors demonstrate that Dlgap4 is strongly expressed in the VZ, and interacts with other VS proteins, including Dlg1 and u03b2-catenin. Searching to explain certain pathogenic mechanisms associated with subependymal and subcortical heterotopia, the authors provide evidence that Dlgap4 interacts with proteins mediating VS integrity, influences the F-actin cytoskeleton, as 10 . . .
  

   

  

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