Novel sterically crowded and conformationally constrained -aminophosphonates with a near-neutral pka as highly accurate 31p nmr ph probes. application to subtle ph gradients determination in dictyostelium discoideum cells

HIGHLIGHTS

  • who: Caroline Delehedde and collaborators from the (UNIVERSITY) have published the paper: Novel Sterically Crowded and Conformationally Constrained -Aminophosphonates with a Near-Neutral pKa as Highly Accurate 31P NMR pH Probes. Application to Subtle pH Gradients Determination in Dictyostelium discoideum Cells, in the Journal: Molecules 2022, 27, 4506. of 25/07/2021
  • what: A novel series of fifteen u03b1-aminophosphonates have been synthesized and screened for their 31 P NMR properties in the probing of subtle pH changes (as low as 0.05 pH units) occurring in normal or acidotic cells.
  • how: In . . .

     

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