HIGHLIGHTS
- who: Beatriz Martu00ednez-Rojas from the (UNIVERSITY) have published the research work: NPC transplantation rescues sci-driven cAMP/EPAC2 alterations, leading to neuroprotection and microglial modulation, in the Journal: (JOURNAL)
- what: The authors demonstrate that severe spinal contusion in adult rats causes transcriptional dysregulation which persists from early subacute to chronic stages of SCI and affects nearly 20 000 genes in total tissue extracts. This study aimed to define alterations to transcriptional profiles during SCI evolution and the molecular processes underlying NPC-based therapies, focusing primarily on cAMP signalling. The authors aimed to transcriptionally evaluate . . .
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