Npgreat: assembly of human subtelomere regions with the use of ultralong nanopore reads and linked-reads

HIGHLIGHTS

  • who: Eleni Adam from the Department of Computer University, Norfolk, VA, USA have published the research work: NPGREAT: assembly of human subtelomere regions with the use of ultralong nanopore reads and linked-reads, in the Journal: (JOURNAL)
  • what: The authors show here that NPGREAT can enhance the completeness and quality of subtelomere assemblies relative to Nanopore reads alone.
  • how: The telomere terminal repeat screen requires the presence of 4 consecutive perfect telomere repeats (24 bases) at least twice at the end of a sequence read and was validated initially for human telomere-containing . . .

     

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