HIGHLIGHTS
- who: . and colleagues from the Helwan University, Egypt Fujita Health University, Japan have published the article: NQO1 protects against clioquinol toxicity, in the Journal: (JOURNAL)
- what: This study identified the early response protein NADPH-quinone-oxidoreductase 1 (NQO1) not only as target but also as a determinant of CQ-induced toxicity in_vitro and in_vivo. The combination of both treatments completely abolished NQO1 activity in the retina . between NQO1 expression and CQ toxicity in_vivo, the authors aimed to reduce visual acuity in adult zebrafish by inhibiting NQO1 activity. This study identified CQ by its ability to . . .
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