HIGHLIGHTS
- who: Manon Douyu00e8re from the (UNIVERSITY) have published the research: NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells, in the Journal: (JOURNAL)
- what: The authors show that NRP1 inhibition by MR438 radiosensitizes MB stem-like cells in vitro. The authors hypothesize that NRP1 inhibition with this new peptidomimetic compound could improve radiotherapy treatment by targeting medulloblastoma stem-like cells, and the authors evaluated the effect of NRP1 inhibition with MR438 concomitant with RT in 3 subgroup MB models (DAOY, D283-Med and D341-Med) by in_vitro experiments on stem-like cells, as . . .
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