HIGHLIGHTS
- who: Carolina Hassibe Thomamp#x000E9 from the DepartmentUniversity of of Minas Gerais, Belo Horizonte, Brazil have published the Article: NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia, in the Journal: Scientific Reports Scientific Reports
- what: The authors performed a knockdown (KD) of the NTAL gene and analyzed its effect on differentiation, apoptosis, autophagy, and mitochondrial function of APL cells (NB4 and NB4-R2), as models of a more genetically and clinically homogeneous AML cell line. The authors show that the knockdown of NTAL reduced mTOR activation and downstream targets . . .
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