Nuclear igf1r interact with pcna to preserve dna replication after dna-damage in a variety of human cancers

HIGHLIGHTS

• who: Chen Yang and colleagues from the Xiangya Hospital of Central South University, Changsha, Hunan, China, Hunan Key have published the research work: Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers, in the Journal: PLOS ONE of July/23,/2020
• what: The authors aimed to describe this mechanism in cancer tissue as well as in cancer cell lines. The authors show that IGF1R interacts with PCNA after irradiation and HU treatment in HeLa cells (cervical cancer cells) and IGF1R positive fibroblasts.
• how: IGF1R . . .
  

   

  

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