Nuclear magnetic resonance approaches in the study of 2-oxo acid dehydrogenase multienzyme complexes—a literature review

HIGHLIGHTS

  • who: Sowmini Kumaran and colleagues from the Department of Chemistry, Rutgers University, Newark, NJ, USA have published the Article: Nuclear Magnetic Resonance Approaches in the Study of 2-Oxo Acid Dehydrogenase Multienzyme Complexesu2014A Literature Review, in the Journal: Molecules 2013, 18, 11873-11903 of 30/07/2013
  • what: In this review the authors report application of NMR-based approaches to both mechanistic and structural issues concerning these These studies revealed the nature and reactivity of transient intermediates on the enzymatic pathway and provided site-specific information on the architecture and binding specificity of the domain . . .

     

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