Nuclear s6k1 enhances oncogenic wnt signaling by inducing wnt/-catenin transcriptional complex formation

HIGHLIGHTS

  • who: Min Gyu Lee and colleagues from the School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea have published the research: Nuclear S6K1 Enhances Oncogenic Wnt Signaling by Inducing Wnt/-Catenin Transcriptional Complex Formation, in the Journal: (JOURNAL)
  • what: The authors show a novel role of S6K1 in regulating the expression of the target genes. The authors aimed to examine how the S6K1 activation affects its interaction with u03b2-catenin.
  • how: The authors performed wound-healing assays and the results showed that the S6K1 deficiency decreased the migratory ability of these two colon . . .

     

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