Nuclear translocation of sgpp-1 and decrease of sgpl-1 activity contribute to sphingolipid rheostat regulation of inflammatory dendritic cells

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  • who: Anja Schwiebs and colleagues from the Institute of General Pharmacology and Toxicology, pharmazentrum frankfurt/ZAFES, Hospital of the Goethe University, Frankfurt, Germany have published the article: Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells, in the Journal: Mediators of Inflammation of 11/Dec/2017
  • what: Despite the obvious importance of S1P-degrading pathways, only a sparse set of investigations focuses on S1P phosphatases during cellular differentiation and cancer, with actually no study dealing with SGPP-1 in immune cells. With the current . . .

     

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