Nucleocytoplasmic transport of active her2 causes fractional escape from the dcis-like state

HIGHLIGHTS

• who: Lixin Wang from the Intraductal xenografts AnimalsFemale, virgin SCID/beige mice (Envigo, ) were obtained at , weeks of age and housed together on a, h dark cycle (, pm, am) and, h light cycle (, am, pm) at, ., u00b0C and, .5% relative humidity. Only female animals were used because breast cancer is very rare in males. All animal work was done in compliance with ethical regulations under University of Virginia IACUC approval #3945, which permitted a maximal tumor size of, ., cm that was not exceeded by this study. For the experiments using doxycycline chow, mice were given a standard . . .
  

   

  

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