HIGHLIGHTS
- who: renata from the aDepartment of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Noskowskiego, Poznan, Poland have published the research work: Nucleoside H-Phosphonates, in the Journal: (JOURNAL)
- how: The best results were obtained when phosphonylation of nucleoside 1a was carried out in pyridine in the presence of 2 equiv. each of DEAD and TPP and by using 2 equiv. of phosphonic acid (Scheme 1). The authors carried out also some preliminary 31P NMR experiments on the formation of H-phosphonate diesters under the Mitsunobu coupling conditions (Scheme 2).
SUMMARY
The Mitsunobu . . .
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