HIGHLIGHTS
- who: Stephen E. Farr from the Laboratory University of have published the Article: Nucleosome plasticity is a critical element of chromatin liquid⠍liquid phase separation and multivalent nucleosome interactions, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 24/Nov/2020
- what: The authors develop an advanced mechanistic multiscale chromatin model designed to investigate the connection between the fine molecular details of nucleosomes (including amino_acid and DNA sequence, specific distributions of posttranslational modifications and epigenetic marks, protein flexibility, DNA mechanical properties, and nucleosome plasticity) and the mesoscale (up to sub-Mb scale) organization of chromatin. To . . .
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