Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion

HIGHLIGHTS

• who: Carina Soares-Cunha from the Physics Department, Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil have published the paper: Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion, in the Journal: (JOURNAL)
• what: The authors show that MSN subpopulations can drive reward and aversion depending on their neuronal stimulation pattern. The authors show that these distinct stimulation protocols elicit divergent electrophysiological responses in downstream targets, the VTA and VP. In agreement, the authors show that intra-VP injection of DOR antagonist abolished the aversive effects of D2-MSN prolonged stimulation (but not . . .
  

   

  

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