Nudcl2 regulates cell migration by stabilizing both myosin-9 and lis1 with hsp90

HIGHLIGHTS

  • who: Wenwen Chen from the (UNIVERSITY) have published the article: NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90, in the Journal: (JOURNAL)
  • what: The works have shown that NudCL2 stabilizes LIS1 (lissencephaly protein 1) by enhancing the interaction between LIS1 and Hsp9018. The authors provide evidence that NudCL2 is required for cell migration regulation. The authors propose that NudCL2 plays an important role in the precise regulation of cell migration by modulating the stability of both myosin-9 and LIS1 with Hsp90, providing a hitherto unrecognized mechanism crucial for cell . . .

     

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