Nudix hydroxylase 15 mutations strongly predict thiopurine-induced leukopenia across different asian ethnicities: implications for screening in a diverse population

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• who: Ida Normiha Hilmi from the Kosugi Hospital, Japan Tokyo Medical and Dental University have published the Article: Nudix Hydroxylase 15 Mutations Strongly Predict Thiopurine-Induced Leukopenia Across Different Asian Ethnicities: Implications for Screening in a Diverse Population, in the Journal: (JOURNAL)
• what: Since thiopurines are commonly used as immunosuppressants in Malaysian patients with IBD, the authors aimed to investigate the association between NUDT15 variations (c.415C > T and c.52G > A) and leukopenia in this multiethnic population. The study shows that the prevalence of NUDT15 c.415C > T is 12.8% in Malaysian patients . . .
  

   

  

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