Nuf2 expression promotes lung adenocarcinoma progression and is associated with poor prognosis

HIGHLIGHTS

  • who: Feng Jiang from the AIMST University, Malaysia have published the paper: NUF2 Expression Promotes Lung Adenocarcinoma Progression and Is Associated With Poor Prognosis, in the Journal: (JOURNAL)
  • what: The authors evaluated the expression of NUF2 in LUAD as described in the following five cohorts:
  • how: The staining results were evaluated by two independent pathologists. RT-qPCR results indicated that si-NUF2 effectively inhibited NUF2 expression in LUAD cell lines . GSEA results showed that NUF2 is involved in proliferation and apoptosis-related pathways including proliferating cell nuclear antigen (PCNA) and TP53 pathways.
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