Numa regulates mitotic spindle assembly, structural dynamics and function via phase separation

HIGHLIGHTS

  • who: Mengjie Sun from the Key LaboratoryPeking University, Beijing, China have published the article: NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Based on the present work, the authors propose a working model to illustrate the role of NuMA in regulating the mitotic spindle assembly, structural dynamics, and function through phase separation (Fig 8). The authors propose that, under the cell cycle control, NuMA initiates phase separation in the nucleus during the mitotic entry in a microtubule-independent way.
  • how: The . . .

     

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