HIGHLIGHTS
- who: Sophie Rousseaux and collaborators from the Institute for Advanced Biosciences, Université Grenoble-Alpes, INSERM, CNRS UMR , have published the research: NUT Is a Driver of p300-Mediated Histone Hyperacetylation: From Spermatogenesis to Cancer, in the Journal: Cancers 2022, 14, 2234. of /2022/
- what: Following this work, and because of its physiological context of expression in male germ cells, the hypothesis was made that NUT could also play a role in histone hyperacetylation associated with genome-wide histone-to-protamine replacement, which occurs in the late phases of spermatogenesis .
- how: These data showed . . .
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